哈里森内科学手册（第19版·英文版） 下载 pdf 百度网盘 epub 免费 2025 电子书 mobi 在线

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本书是《哈里森内科学（第19版）》的减缩版口袋书，内容涵盖病因与流行病学、临床相关病理生理学、症状与体征、诊断与鉴别诊断、体格检查与实验室检查、诊疗要点、实用指南等，着重呈现了医学实践中常见疾病的临床表现、诊断和治疗要点，写作特点突出。本书以全彩、简洁实用、方便携带为特色，为临床诊疗、查房提供速查资料。

Contributors................................................xv

Preface...................................................xvii

Acknowledgments..........................................xix

SECTION 1 CARE OF THE HOSPITALIZED PATIENT

1 Electrolytes/Acid-Base Balance....................................................1

2 Diagnostic Imaging in Internal Medicine..................................23

3 Procedures Commonly Performed by Internists......................26

4 Principles of Critical Care Medicine...........................................31

5 Pain and Its Management...........................................................35

6 Assessment of Nutritional Status...............................................40

7 Enteral and Parenteral Nutrition...............................................43

8 Transfusion and Pheresis Therapy.............................................46

9 Palliative and End-of-Life Care...................................................48

SECTION 2 MEDICAL EMERGENCIES

10 Cardiovascular Collapse and Sudden Death.............................57

11 Shock............................................................................................61

12 Sepsis and Septic Shock..............................................................65

13 Acute Pulmonary Edema............................................................69

14 Acute Respiratory Distress Syndrome.......................................71

15 Respiratory Failure......................................................................73

16 Confusion, Stupor, and Coma....................................................76

17 Stroke...........................................................................................82

18 Subarachnoid Hemorrhage........................................................91

19 Increased Intracranial Pressure and Head Trauma..................93

20 Spinal Cord Compression...........................................................98

21 Hypoxic-Ischemic Encephalopathy..........................................100

22 Status Epilepticus......................................................................101

23 Diabetic Ketoacidosis and Hyperosmolar Coma....................104

24 Hypoglycemia............................................................................107

25 Oncologic Emergencies.............................................................109

26 Anaphylaxis...............................................................................114

27 Bites, Venoms, Stings, and Marine Poisonings.......................115

SECTION 3 COMMON PATIENT PRESENTATIONS

28 Fever, Hyperthermia, and Rash................................................127

29 Generalized Fatigue..................................................................131

30 Weight Loss................................................................................135

31 Chest Pain..................................................................................137

32 Palpitations................................................................................141

33 Dyspnea......................................................................................142

34 Cyanosis.....................................................................................145

35 Cough and Hemoptysis.............................................................146

36 Edema.........................................................................................150

37 Abdominal Pain.........................................................................154

38 Nausea, Vomiting, and Indigestion.........................................158

39 Dysphagia..................................................................................162

40 Diarrhea, Malabsorption, and Constipation...........................167

41 Gastrointestinal Bleeding.........................................................174

42 Jaundice and Evaluation of Liver Function.............................178

43 Ascites........................................................................................187

44 Lymphadenopathy and Splenomegaly...................................189

45 Anemia and Polycythemia........................................................194

46 Azotemia and Urinary Abnormalities......................................197

47 Pain and Swelling of Joints.......................................................203

48 Back and Neck Pain...................................................................207

49 Headache...................................................................................215

50 Syncope......................................................................................222

51 Dizziness and Vertigo...............................................................226

52 Acute Visual Loss and Double Vision......................................229

53 Weakness and Paralysis............................................................233

54 Tremor and Movement Disorders............................................236

55 Aphasia.......................................................................................239

56 Sleep Disorders..........................................................................241

57 Dysuria and Bladder Pain.........................................................245

SECTION 4 OTOLARYNGOLOGY

58 Sore Throat, Earache, and Upper

Respiratory Symptoms.............................................................247

SECTION 5 DERMATOLOGY

59 General Examination of the Skin.............................................255

60 Common Skin Conditions.........................................................258

SECTION 6 HEMATOLOGY AND ONCOLOGY

61 Examination of Blood Smears and Bone Marrow...................265

62 Red Blood Cell Disorders..........................................................267

63 Leukocytosis and Leukopenia..................................................274

64 Bleeding and Thrombotic Disorders.......................................277

65 Myeloid Leukemias, Myelodysplasia, and

Myeloproliferative Syndromes................................................283

66 Lymphoid Malignancies............................................................293

67 Skin Cancer................................................................................305

68 Head and Neck Cancer..............................................................308

69 Lung Cancer...............................................................................310

70 Breast Cancer.............................................................................316

71 Tumors of the Gastrointestinal Tract......................................321

72 Genitourinary Tract Cancer......................................................333

73 Gynecologic Cancer...................................................................338

74 Prostate Hyperplasia and Carcinoma......................................342

75 Cancer of Unknown Primary Site.............................................345

76 Paraneoplastic Endocrine Syndromes.....................................348

77 Neurologic Paraneoplastic Syndromes...................................352

SECTION 7 INFECTIOUS DISEASES

78 Infections Acquired in Health Care Facilities..........................357

79 Infections in the Immunocompromised Host.........................362

80 Infective Endocarditis...............................................................372

81 Intraabdominal Infections........................................................382

82 Infectious Diarrheas..................................................................386

83 Sexually Transmitted and Reproductive Tract Infections.....399

84 Infections of the Skin, Soft Tissues, Joints, and Bones..........415

85 Pneumococcal Infections..........................................................422

86 Staphylococcal Infections.........................................................425

87 Streptococcal/Enterococcal Infections, Diphtheria,

and Infections Caused by Other Corynebacteria

and Related Species..................................................................434

88 Meningococcal and Listerial Infections...................................443

89 Infections Caused by Haemophilus, Bordetella,

Moraxella, and HACEK Group Organisms...............................448

90 Diseases Caused by Gram-Negative Enteric

Bacteria and Pseudomonas.......................................................453

91 Infections Caused by Miscellaneous

Gram-Negative Bacilli...............................................................462

92 Anaerobic Infections.................................................................469

93 Nocardiosis, Actinomycosis, and Whipple’s Disease.............477

94 Tuberculosis and Other Mycobacterial Infections.................482

95 Lyme Disease and Other Nonsyphilitic

Spirochetal Infections...............................................................494

96 Rickettsial Diseases...................................................................500

97 Mycoplasma pneumoniae, Legionella Species, and

Chlamydia pneumoniae.............................................................510

98 Chlamydia trachomatis and C. psittaci.....................................514

99 Herpesvirus Infections..............................................................516

100 Cytomegalovirus and Epstein-Barr Virus Infections..............525

101 Influenza and Other Viral Respiratory Diseases.....................530

102 Rubeola, Rubella, Mumps, and Parvovirus Infections...........538

103 Enteroviral Infections................................................................543

104 Insect- and Animal-Borne Viral Infections..............................546

105 HIV Infection and AIDS.............................................................554

106 Fungal Infections.......................................................................568

107 Pneumocystis Infections............................................................583

108 Protozoal Infections..................................................................586

109 Helminthic Infections and Ectoparasite

Infestations................................................................................599

SECTION 8 CARDIOLOGY

110 Physical Examination of the Heart...........................................613

111 Electrocardiography.................................................................618

112 Noninvasive Examination of the Heart...................................622

113 Congenital Heart Disease in the Adult....................................627

114 Valvular Heart Disease..............................................................632

115 Cardiomyopathies and Myocarditis........................................639

116 Pericardial Disease....................................................................644

117 Hypertension.............................................................................649

118 Metabolic Syndrome.................................................................656

119 ST-Segment Elevation Myocardial

Infarction....................................................................................658

120 Unstable Angina and Non-ST-Elevation

Myocardial Infarction................................................................668

121 Chronic Stable Angina..............................................................672

122 Bradyarrhythmias.....................................................................677

123 Tachyarrhythmias.....................................................................679

124 Heart Failure and Cor Pulmonale.............................................687

125 Diseases of the Aorta................................................................693

126 Peripheral Vascular Disease.....................................................696

127 Pulmonary Hypertension..........................................................699

SECTION 9 PULMONOLOGY

128 Respiratory Function and Pulmonary

Diagnostic Procedures..............................................................705

129 Asthma.......................................................................................711

130 Environmental Lung Diseases..................................................715

131 Chronic Obstructive Pulmonary Disease.................................718

132 Pneumonia, Bronchiectasis, and Lung Abscess......................722

133 Pulmonary Thromboembolism and Deep-Vein

Thrombosis................................................................................730

134 Interstitial Lung Disease...........................................................734

135 Diseases of the Pleura and Mediastinum................................740

136 Disorders of Ventilation............................................................744

137 Sleep Apnea...............................................................................745

SECTION 10 NEPHROLOGY

138 Acute Renal Failure...................................................................747

139 Chronic Kidney Disease and Uremia........................................752

140 Dialysis.......................................................................................754

141 Renal Transplantation..............................................................756

142 Glomerular Diseases.................................................................759

143 Renal Tubular Disease...............................................................769

144 Urinary Tract Infections and Interstitial Cystitis....................775

145 Nephrolithiasis..........................................................................779

146 Urinary Tract Obstruction.........................................................782

SECTION 11 GASTROENTEROLOGY

147 Peptic Ulcer and Related Disorders.........................................785

148 Inflammatory Bowel Diseases..................................................790

149 Colonic and Anorectal Diseases...............................................794

150 Cholelithiasis, Cholecystitis, and Cholangitis.........................799

151 Pancreatitis................................................................................804

152 Acute Hepatitis..........................................................................809

153 Chronic Hepatitis.......................................................................816

154 Cirrhosis and Alcoholic Liver Disease......................................826

155 Portal Hypertension..................................................................831

SECTION 12 ALLERGY, CLINICAL IMMUNOLOGY, AND RHEUMATOLOGY

156 Diseases of Immediate-Type Hypersensitivity.......................835

157 Primary Immune Deficiency Diseases.....................................840

158 Systemic Lupus Erythematosus, Rheumatoid Arthritis,

and Other Connective Tissue Diseases....................................843

159 Vasculitis....................................................................................850

160 Ankylosing Spondylitis.............................................................854

161 Psoriatic Arthritis.......................................................................857

162 Reactive Arthritis.......................................................................859

163 Osteoarthritis.............................................................................861

164 Gout, Pseudogout, and Related Diseases...............................863

165 Other Musculoskeletal Disorders.............................................867

166 Sarcoidosis.................................................................................870

167 Amyloidosis...............................................................................873

SECTION 13 ENDOCRINOLOGY AND METABOLISM

168 Disorders of the Anterior Pituitary and Hypothalamus.........877

169 Diabetes Insipidus and Syndrome of Inappropriate

Antidiuretic Hormone...............................................................883

170 Thyroid Gland Disorders...........................................................886

171 Adrenal Gland Disorders..........................................................895

172 Obesity.......................................................................................901

173 Diabetes Mellitus.......................................................................904

174 Disorders of the Male Reproductive System...........................912

175 Disorders of the Female Reproductive System......................917

176 Hypercalcemia and Hypocalcemia...........................................924

177 Osteoporosis and Osteomalacia..............................................931

178 Hypercholesterolemia and Hypertriglyceridemia..................936

179 Hemochromatosis, Porphyrias, and Wilson’s Disease...........942

SECTION 14 NEUROLOGY

180 The Neurologic Examination....................................................947

181 Seizures and Epilepsy...............................................................956

182 Dementia....................................................................................968

183 Parkinson’s Disease...................................................................976

184 Ataxic Disorders........................................................................981

185 ALS and Other Motor Neuron Diseases...................................984

186 Autonomic Nervous System Disorders....................................988

187 Trigeminal Neuralgia, Bell’s Palsy, and

Other Cranial Nerve Disorders.................................................995

188 Spinal Cord Diseases.............................................................. 1002

189 Tumors of the Nervous System............................................. 1008

190 Multiple Sclerosis................................................................... 1012

191 Acute Meningitis and Encephalitis....................................... 1020

192 Chronic and Recurrent Meningitis........................................ 1031

193 Peripheral Neuropathies, Including

Guillain-Barré Syndrome....................................................... 1040

194 Myasthenia Gravis.................................................................. 1050

195 Muscle Diseases...................................................................... 1053

SECTION 15 PSYCHIATRY AND SUBSTANCE ABUSE

196 Psychiatric Disorders............................................................. 1063

197 Psychiatric Medications......................................................... 1071

198 Eating Disorders..................................................................... 1079

199 Alcohol Use Disorder.............................................................. 1080

200 Narcotic Abuse........................................................................ 1084

SECTION 16 DISEASE PREVENTION AND HEALTH MAINTENANCE

201 Routine Disease Screening.................................................... 1087

202 Cardiovascular Disease Prevention...................................... 1092

203 Prevention and Early Detection of Cancer........................... 1094

204 Smoking Cessation................................................................. 1102

205 Women’s Health..................................................................... 1104

SECTION 17 ADVERSE DRUG REACTIONS

206 Adverse Drug Reactions........................................................ 1107

Index................................................................................................. 1109

Dennis L.Kasper 博士是威廉埃勒里钱宁的医学教授；任哈佛医学院微生物学与免疫生物学系免疫分部微生物学和免疫生物学教授；同时在马萨诸塞州的波士顿布莱根妇女医院任职。

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书籍介绍

最经典、最权威、最前沿的内科学参考书

◎ 编辑推荐

☆ 涵盖病因与流行病学、临床相关病理生理学知识、症状与体征、诊断与鉴别诊断、体格检查与实验室检查、诊疗要点和实用指南等内容

☆ 传播医学知识的同时，引导读者的逻辑思维

☆ 高水平学术审核，使本书保持专业领先水平

☆ 调理清晰的流程图及表格使查阅更高效

☆ 全彩、简洁、便携

◎ 内容简介

本书是《哈里森内科学（第19版）》的减缩版口袋书，内容涵盖病因与流行病学、临床相关病理生理学、症状与体征、诊断与鉴别诊断、体格检查与实验室检查、诊疗要点、实用指南等，着重呈现了医学实践中常见疾病的临床表现、诊断和治疗要点，写作特点突出。本书以全彩、简洁实用、方便携带为特色，为临床诊疗、查房提供速查资料。